Couverture / Jaquette

The second edition of this popular textbook written for undergraduates, graduate students, and medical researchers, Genetics and Genomics in Medicine explains the science behind the uses of genetics and genomics in medicine today. This second edition has been thoroughly updated in line with the latest developments in the field.

Note biographique

Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, UK. Together with a former colleague, Andrew Read, he writes the popular Human Molecular Genetics textbook, now in its Fifth Edition.

Anneke Lucassen is Professor of Genomic Medicine and Director of the Centre for Personalised Medicine at the University of Oxford, UK

Table des matières

1. Fundamentals of DNA, Chromosomes, and Cells
2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization
3. Principles Underlying Core DNA Technologies
4. Principles of Genetic Variation
5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies
6. Principles of Gene Regulation and Epigenetics
7. How Genetic Variation in DNA and Chromosomes Causes Disease
8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease
9. Genetic Approaches to Treating Disease
10. Cancer Genetics and Genomics
11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects

Détails